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Biological and Bio-Medical Sciences (5 job listings)

  • POSTDOCTORAL FELLOW IN CANCER IMMUNOLOGY AND IMMUNOTHERAPY

    Date posted: 09/13/17
    Description:

    A postdoctoral position is available in the Division of Surgical Oncology, Department of Surgery at the University of California, Los Angeles (UCLA) to work in the laboratory of Dr. Manuel L. Penichet.

    We are affiliated with the Department of Microbiology, Immunology, and Molecular Genetics and the Jonsson Comprehensive Cancer Center at UCLA.

    We are looking for a highly motivated postdoctoral fellow to join our research team working on cancer immunology and immunotherapy, including the development and characterization of new antibodies for the therapy of cancer. We work in the new field of AllergoOncology, which aims to reveal the function of immune responses elicited by antibodies of the IgE class in the context of cancer, and to develop novel IgE-based treatment options against malignant diseases. In addition, we are interested in developing new generations of antibodies of the IgG class and their derivatives, such as antibody fusion proteins, to be used as drug delivery systems and novel anti-proliferative/pro-apoptotic agents against cancer cells. Our projects have a basic science (mechanistic) component and translational potential.

    Applicants should hold M.D. degree and/or Ph.D. degree in Biological Sciences. Fluency in English and strong written and oral communication skills are pre-requisites; US permanent residency or citizenship is preferred but not required.

    Interested individuals should send (e-mail) their CV, a brief description of their research experience, a statement of research interests, and a list of three references to:


    Manuel L. Penichet, M.D., Ph.D.
    Professor of Surgery, Microbiology,
    Immunology, and Molecular Genetics
    Division of Surgical Oncology, Department of Surgery
    University of California, Los Angeles (UCLA).
    10833 Le Conte Ave, CHS 54-117
    Los Angeles, CA 90095
    Telephone (lab): (310) 825-0457
    Telephone (office): (310) 825-1304
    Fax: (310) 825-7575
    E-mail: penichet@mednet.ucla.edu


  • Chemistry Postdoctoral Position at UCLA

    Date posted: 09/13/17
    Description:

    A unique opportunity for a postdoctoral scholar is currently available at the Crump Institute for Molecular Imaging at the University of California Los Angeles (UCLA). Our team has joined forces with Fuzionaire Diagnostics, a Caltech spin-out company from the laboratory of Prof Bob Grubbs, founded by Anton Toutov (PhD ’16). The Crump Institute provides a unique environment of translational research that aims to develop new technologies to examine the biology of disease, improve molecular diagnostic tools and advance therapeutic developments. Research focuses around positron emission tomography (PET), a powerful imaging tool that provides non-invasive, quantitative information about specific molecular targets and interactions in living organisms and patients. Molecular imaging is emerging as an essential part of cancer research and clinical care particularly by providing tools for better understanding the biology of disease and its therapeutic modulation.

    We are currently seeking a motivated synthetic chemist ready to function in a fast-paced and collaborative environment. The synthetic chemistry candidate for this opportunity will work on novel methods for the synthesis of PET tracers to be evaluated for clinical translation at the Crump Institute for Molecular Imaging. This candidate will be part of the Murphy group in the Crump Institute and work closely with the Fuzionaire Diagnostics team as well. The goals will be to develop and optimize synthetic routes for the synthesis of [18F]-labeled small-molecules as well as biologics like peptides, proteins and antibodies for pre-clinical imaging studies. Experience in radiochemistry is not required; training will be provided for radiosynthesis with 18F using automated commercial radiosynthesizers. Applicants should have exceptional communication skills coupled with a strong publication record.

    Qualifications:
    • Ph.D. in Organic Chemistry required with a strong publication record in peer reviewed journals
    • Sound knowledge of organic chemistry reactions, mechanisms, multistep synthesis, and purification techniques
    • Must be able to prioritize work, multi-task and be very well organized
    • Effective problem solving skills
    • Must have demonstrated awareness of safety practices required for working with hazardous chemicals
    • Excellent communication skills (oral and written) with strong work ethic
    • Highly motivated and demonstrates the ability to work efficiently and productively in a dynamic team environment with other scientific disciplines
    • Experience in fluorine and organometallic chemistry is highly desirable

    Interested applicants please send a cover letter and curriculum vitae (CV) to Jennifer Murphy at JMMurphy@mednet.ucla.edu.

    The University of California is an Equal Opportunity/Affirmative Action Employer advancing inclusive excellence. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, age, protected veteran status, or other protected categories covered by the UC nondiscrimination policy. UC Nondiscrimination & Affirmative Action Policy


  • Post-doctoral fellowship in an Immunology lab at UCLA

    Date posted: 08/30/17
    Description: Post-doctoral Fellow – Butte Lab

    We are seeking an experienced applicant for a post-doctoral fellowship in an Immunology lab at UCLA (Department of Pediatrics, Division of Immunology, Allergy, and Rheumatology). Applicants need to have experience in immunology and intravital 2-photon microscopy. The project entails visualizing immune responses to infections, autoimmunity, and cancer. Applicants should be self-motivated with a track record of publication, have laboratory and analytical skills, and be a critical thinker.

    Qualifications:

    • PhD or MD/PhD in Immunology or related field of study less than 5 years from completion of Ability to work simultaneously on multiple projects and quickly adapt to new tasks
    • Excellent communication skills and ability to work with other scientists
    • Ability to function independently in the laboratory
    Skills:
    • Deep capabilities in intravital 2-photon microscopy and common immunology techniques
    • Must be comfortable working with mice
    • Experience in image analysis software (e.g., Imaris)
    • Strong analytical skills, including statistics
    • Meticulous laboratory technique, record keeping, and data management
    • Experience with retroviral transduction techniques highly desirable
    • Experience with molecular biology techniques desirable
    Duties and Responsibilities:
    • Conducting research as determined with Principal Investigator (PI)
    • Contribute to writing grants with the PI
    • Publish results of laboratory research in collaboration with PI, including writing scientific manuscripts, abstracts and other supporting documentation
    • Participate in laboratory and other seminars, meetings, educational sessions, general and specific safety training and other training sessions
    • Provide mentorship and teaching to other members of the lab, which comprises of PhD or MD students, post-docs, undergraduate students and summer students
    • Performs other duties and laboratory responsibilities as requested

    Contacts:
    Manish Butte: mbutte@mednet.ucla.edu
    Timothy Thauland: tthauland@mednet.ucla.edu


  • Pediatrics Infectious Diseases Post Doctoral Employee or Fellow

    Date posted: 05/15/17
    Information:Seeking an experienced Ph.D. or M.D./Ph.D. for a Post Doctoral fellowship with an interest in HIV-1 infection and in the microbiome as it relates to human health and disease . The post doctoral fellow will work in the Pediatrics Division of Infectious Diseases at UCLA with Dr. Aldrovandi. Applicants need to have a Ph.D preferably in molecular biology or virology.
    Description:

    Department: Pediatrics Infectious Diseases

    Description:

    Seeking an experienced Ph.D. or M.D./Ph.D. for a Post Doctoral fellowship with an interest in HIV-1 infection and in the microbiome as it relates to human health and disease. The post doctoral fellow will work in the Pediatrics Division of Infectious Diseases at UCLA with Dr. Aldrovandi. Applicants need to have a Ph.D preferably in molecular biology or virology.

    Requirements:


    Qualifications:

    • Doctor of Philosophy in Molecular Biology or Virology or related field of study less than 5 years from completion of PhD
    • Solid understanding of molecular biology and common laboratory approaches in molecular biology
    • Ability to work simultaneously on multiple projects and quickly adapt to new tasks
    • Excellent communication skills and ability to work with computational and experimental scientists
    • Ability to function independently in the laboratory

    Skills:

    • DNA, RNA and protein extractions
    • Sterile technique
    • Meticulous laboratory technique
    • Experience in PCR, cloning, Next-Generation Sequencing desired
    • Working knowledge of laboratory notebook management and data management
    • Must be comfortable working with human pathogens and human samples including blood, stool, urine, saliva, cervicovaginal lavage samples, and more.

    Duties and Responsibilities:

    • Conducting research as determined with Principal Investigator (PI)
    • Publish results of independent laboratory research in collaboration with lab PI, including writing of scientific manuscripts, abstracts and other supporting documentation
    • Participate in laboratory and Divisional seminars, meetings, educational sessions, general and specific safety training and other training sessions
    • Provide mentorship and teaching to other members of the lab which is comprised of PhD or MD students, post-docs, undergraduate students and summer students.
    • Performs other duties and laboratory responsibilities as requested.

    Contact Person(s):

    Nicole H. Tobin, M.D.
    Pediatrics/Pediatric Infectious Diseases
    University of California, Los Angeles
    675 Charles E. Young Drive South
    MacDonald Research Laboratory (MRL), 4-629
    Los Angeles, CA 90095
    (310) 825-7708
    Email: NTobin@mednet.ucla.edu


  • Postdoctoral Enrichment Program

    Date posted: 11/02/16
    Information:Join some of your UCLA postdoctoral colleagues with support from the Burroughs Wellcome Fund for the Postdoctoral Enrichment Program for underrepresented minority postdocs.
    Description: About the Award The Postdoctoral Enrichment Program (PDEP) provides a total of $60,000 over three years to support the career development activities for underrepresented minority postdoctoral fellows in a degree-granting institution (an institution includes its affiliated graduate and medical schools, hospitals and research institutions) in the United States or Canada whose training and professional development are guided by mentors committed to helping them advance to stellar careers in biomedical or medical research. Details Generally, up to 12 awards will be granted for enrichment activities annually. This grant is meant to supplement the training of postdocs whose research activities are already supported. It is not a research grant. The program provides a total of $60,000 over three years as follows: •Year one: $20,000 will be granted to support enrichment activities of the postdoctoral fellow ($10,000 for research supplies or equipment uniquely required to enhance the postdoctoral fellow’s research and $10,000 for education and training, including for mentors in the research lab where the postdoctoral fellow is assigned.) The PDEP award cannot be used to support salary expenses or indirect costs. (Refer to Terms of Grant for information on indirect costs and other requirements for use of funds.) •Year two: $20,000 (same allocation as year one) •Year three: $20,000 will be granted to help the postdoctoral fellow advance research efforts towards the professoriate. The funds must be used to develop independent, innovative areas of research. Eligibility For a full explanation of the eligibility requirements, view Request for Proposals. Questions Email Alfred Mays or Melanie Scott with "2017 PDEP" as the subject line.


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