John S. Adams, M.D

John S. Adams

Professor, Medicine, Molecular, Cell, and Developmental Biology, Orthopaedic Surgery Vice-Chair, Research, Orthopaedic Surgery Director, Orthopaedic Hospital Research Center Associate Director, CTSI Member, Eli & Edythe Broad Center of Regenerative Medicine & Stem Cell Research

Full
310-267-5585

Laboratory Address:
615 Charles E. Young Drive South
Room 446
Los Angeles, CA 90095

Office Address:
615 Charles E. Young Drive South
Room 410E
Los Angeles, CA 90095

Website

Dr. Adams is board certified in internal medicine and endocrinology, diabetes and metabolism. Dr. Adams has focused his research on sterol synthesis and metabolism, vitamin D and steroid hormone action, and osteoporosis. His research has been published in numerous peer-reviewed journals, including Nature, Science, Cell, Endocrinology, Molecular Endocrinology, Journal of Clinical Endocrinology and Metabolism, Journal of of Clinical Investigation, Annals of Internal Medicine and The New England Journal of Medicine. Dr. Adams serves as Associate Editor for the Journal of Bone and Mineral Research and on the editorial board for the Journal of Clinical Endocrinology and Metabolism. Dr. Adams is an active member of several professional committees on the national scene. He currently serves on the Skeletal Biology Development and Disease, the Orthopedic Study Section for grant review at the National Institute for Arthritis and Musculoskeletal Diseases of the National Institutes of Health. Dr. Adams received his bachelor’s degree from the University of Kansas and his medical degree from the University of Kansas School of Medicine. He completed his fellowship in endocrinology and internal medicine at Massachusetts General Hospital, Harvard Medical School.

 

A selected list of publications:

Chun Rene F, Hernandez Ivan, Pereira Renata, Swinkles Leon, Huijs Tonnie, Zhou Rui, Liu Nancy Q, Shieh Albert, Guemes Miriam, Mallya Sanjay M, Adams John S, Hewison Martin   Differential responses to vitamin D2 and vitamin D3 are associated with variations in free 25-hydroxyvitamin D Endocrinology, 2016; 28(4): en20161139.
Shieh Albert, Chun Rene F, Ma Christina, Witzel Sten, Meyer Briana, Rafison Brandon, Swinkels Leon, Huijs Tonnie, Pepkowitz Sam, Holmquist Brett, Hewison Martin, Adams John S   Effects of high-dose vitamin D2 versus vitamin D3 on total and free 25-hydroxyvitamin D and markers of calcium balance The Journal of clinical endocrinology and metabolism, 2016; 28(4): jc20161871.
Nielson Carrie M, Jones Kerry S, Chun Rene F, Jacobs Jon M, Wang Ying, Hewison Martin, Adams John S, Swanson Christine M, Lee Christine G, Vanderschueren Dirk, Pauwels Steven, Prentice Ann, Smith Richard D, Shi Tujin, Gao Yuqian, Schepmoes Athena A, Zmuda Joseph M, Lapidus Jodi, Cauley Jane A, Bouillon Roger, Schoenmakers Inez, Orwoll Eric S, Orwoll Eric S   Free 25-Hydroxyvitamin D: Impact of Vitamin D Binding Protein Assays on Racial-Genotypic Associations The Journal of clinical endocrinology and metabolism, 2016; 101(5): 2226-34.
Jenkinson Carl, Taylor Angela E, Hassan-Smith Zaki K, Adams John S, Stewart Paul M, Hewison Martin, Keevil Brian G   High throughput LC-MS/MS method for the simultaneous analysis of multiple vitamin D analytes in serum Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2016; 1014(17): 56-63.
Nielson Carrie M, Jones Kerry S, Bouillon Roger, Bouillon Roger, Chun Rene F, Jacobs Jon, Wang Ying, Hewison Martin, Adams John S, Swanson Christine M, Lee Christine G, Vanderschueren Dirk, Pauwels Steven, Prentice Ann, Smith Richard D, Shi Tujin, Gao Yuqian, Zmuda Joseph M, Lapidus Jodi, Cauley Jane A, Schoenmakers Inez, Orwoll Eric S   Role of Assay Type in Determining Free 25-Hydroxyvitamin D Levels in Diverse Populations The New England journal of medicine, 2016; 374(17): 1695-6.
Zhang Shu, Ba Kai, Wu Ling, Lee Siyong, Peault Bruno, Petrigliano Frank A, McAllister David R, Adams John S, Evseenko Denis, Lin Yunfeng   Adventitial Cells and Perictyes Support Chondrogenesis Through Different Mechanisms in 3-Dimensional Cultures With or Without Nanoscaffolds Journal of biomedical nanotechnology, 2015; 11(10): 1799-807.
James Aaron W, Shen Jia, Zhang Xinli, Asatrian Greg, Goyal Raghav, Kwak Jin H, Jiang Lin, Bengs Benjamin, Culiat Cymbeline T, Turner A Simon, Seim Iii Howard B, Wu Benjamin M, Lyons Karen, Adams John S, Ting Kang, Soo Chia   NELL-1 in the treatment of osteoporotic bone loss Nature communications, 2015; 6: 7362.
Lake Jordan E, Hoffman Risa M, Tseng Chi-Hong, Wilhalme Holly M, Adams John S, Currier Judith S   Success of Standard Dose Vitamin D Supplementation in Treated Human Immunodeficiency Virus Infection Open forum infectious diseases, 2015; 2(2): ofv068.
Zhou Rui, Chun Rene F, Lisse Thomas S, Garcia Alejandro J, Xu Jianzhong, Adams John S, Hewison Martin   Vitamin D and alternative splicing of RNA The Journal of steroid biochemistry and molecular biology, 2015; 148: 310-7.
Chun Rene F, Liu Nancy Q, Lee T, Schall Joan I, Denburg Michelle R, Rutstein Richard M, Adams John S, Zemel Babette S, Stallings Virginia A, Hewison Martin   Vitamin D supplementation and antibacterial immune responses in adolescents and young adults with HIV/AIDS The Journal of steroid biochemistry and molecular biology, 2015; 148: 290-7.
Chun Rene F, Blatter Elizabeth, Elliott Stephanie, Fitz-Gibbon Sorel, Rieger Sandra, Sagasti Alvaro, Adams John S, Hewison Martin   Cloning of a functional 25-hydroxyvitamin D-1α-hydroxylase in zebrafish (Danio rerio) Cell biochemistry and function, 2014; 32(8): 675-82.
Wu Ling, Gonzalez Stephanie, Shah Saumya, Kyupelyan Levon, Petrigliano Frank A, McAllister David R, Adams John S, Karperien Marcel, Tuan Tai-Lan, Benya Paul D, Evseenko Denis   Extracellular matrix domain formation as an indicator of chondrocyte dedifferentiation and hypertrophy Tissue engineering. Part C, Methods, 2014; 20(2): 160-8.
Montoya Dennis, Inkeles Megan S, Liu Phillip T, Realegeno Susan, Teles Rosane M B, Vaidya Poorva, Munoz Marcos A, Schenk Mirjam, Swindell William R, Chun Rene, Zavala Kathryn, Hewison Martin, Adams John S, Horvath Steve, Pellegrini Matteo, Bloom Barry R, Modlin Robert L   IL-32 is a molecular marker of a host defense network in human tuberculosis Science translational medicine, 2014; 6(250): 250ra114.
Chun Rene F, Liu Philip T, Modlin Robert L, Adams John S, Hewison Martin   Impact of vitamin D on immune function: lessons learned from genome-wide analysis Frontiers in physiology, 2014; 5(2): 151.
Lisse Thomas S, Vadivel Kanagasabai, Bajaj S Paul, Chun Rene F, Hewison Martin, Adams John S   The heterodimeric structure of heterogeneous nuclear ribonucleoprotein C1/C2 dictates 1,25-dihydroxyvitamin D-directed transcriptional events in osteoblasts Bone research, 2014; 2(250): .
Yuan Feng-Ning F, Valiyaparambil Jayasanker, Woods Michael C, Tran Huy, Pant Rima, Adams John S, Mallya Sanjay M   Vitamin D signaling regulates oral keratinocyte proliferation in vitro and in vivo International journal of oncology, 2014; 44(5): 1625-33.
Bacchetta Justine, Sea Jessica L, Chun Rene F, Lisse Thomas S, Wesseling-Perry Katherine, Gales Barbara, Adams John S, Salusky Isidro B, Hewison Martin   Fibroblast growth factor 23 inhibits extrarenal synthesis of 1,25-dihydroxyvitamin D in human monocytes Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 2013; 28(1): 46-55.
Wu Ling, Bluguermann Carolina, Kyupelyan Levon, Latour Brooke, Gonzalez Stephanie, Shah Saumya, Galic Zoran, Ge Sundi, Zhu Yuhua, Petrigliano Frank A, Nsair Ali, Miriuka Santiago G, Li Xinmin, Lyons Karen M, Crooks Gay M, McAllister David R, Van Handel Ben, Adams John S, Evseenko Denis   Human developmental chondrogenesis as a basis for engineering chondrocytes from pluripotent stem cells Stem cell reports, 2013; 1(6): 575-89.
Adams John S, Ramin Jonathan, Rafison Brandon, Windon Charles, Windon Annika, Liu Philip T   Redefining Human Vitamin D Sufficiency: Back to the Basics Bone research, 2013; 1(1): 2-10.
Adams John S, Rafison Brandon, Witzel Sten, Reyes Rachel E, Shieh Albert, Chun Rene, Zavala Kathryn, Hewison Martin, Liu Philip T   Regulation of the extrarenal CYP27B1-hydroxylase The Journal of steroid biochemistry and molecular biology, 2013; 5(2): .
Teles Rosane M B, Graeber Thomas G, Krutzik Stephan R, Montoya Dennis, Schenk Mirjam, Lee Delphine J, Komisopoulou Evangelia, Kelly-Scumpia Kindra, Chun Rene, Iyer Shankar S, Sarno Euzenir N, Rea Thomas H, Hewison Martin, Adams John S, Popper Stephen J, Relman David A, Stenger Steffen, Bloom Barry R, Cheng Genhong, Modlin Robert L   Type I interferon suppresses type II interferon-triggered human anti-mycobacterial responses Science (New York, N.Y.), 2013; 339(6126): 1448-53.
Lisse Thomas S, Chun Rene F, Rieger Sandra, Adams John S, Hewison Martin   Vitamin D activation of functionally distinct regulatory miRNAs in primary human osteoblasts Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 2013; 339(6126): .
Chun Rene F, Peercy Bradford E, Orwoll Eric S, Nielson Carrie M, Adams John S, Hewison Martin   Vitamin D and DBP: The free hormone hypothesis revisited The Journal of steroid biochemistry and molecular biology, 2013; 5(2): .
Lisse Thomas S, Adams John S, Hewison Martin   Vitamin D and microRNAs in bone Critical reviews in eukaryotic gene expression, 2013; 23(3): 195-214.
James Aaron W, Pang Shen, Askarinam Asal, Corselli Mirko, Zara Janette N, Goyal Raghav, Chang Le, Pan Angel, Shen Jia, Yuan Wei, Stoker David, Zhang Xinli, Adams John S, Ting Kang, Soo Chia   Additive Effects of Sonic Hedgehog and Nell-1 Signaling in Osteogenic Versus Adipogenic Differentiation of Human Adipose-Derived Stromal Cells Stem cells and development, 2012; .
Adams J S, Hewison M   Extrarenal expression of the 25-hydroxyvitamin D-1-hydroxylase Archives of biochemistry and biophysics, 2012; .
Billi Fabrizio, Benya Paul, Kavanaugh Aaron, Adams John, McKellop Harry, Ebramzadeh Edward   The John Charnley Award: an accurate and extremely sensitive method to separate, display, and characterize wear debris: part 2: metal and ceramic particles Clinical orthopaedics and related research, 2012; 470(2): 339-50.
Billi Fabrizio, Benya Paul, Kavanaugh Aaron, Adams John, Ebramzadeh Edward, McKellop Harry   The John Charnley Award: an accurate and sensitive method to separate, display, and characterize wear debris: part 1: polyethylene particles Clinical orthopaedics and related research, 2012; 470(2): 329-38.
Rosen Clifford J, Adams John S, Bikle Daniel D, Black Dennis M, Demay Marie B, Manson Joann E, Murad M Hassan, Kovacs Christopher S   The Nonskeletal Effects of Vitamin D: An Endocrine Society Scientific Statement Endocrine reviews, 2012; .
Chun Rene F, Peercy Bradford E, Adams John S, Hewison Martin   Vitamin D binding protein and monocyte response to 25-hydroxyvitamin D and 1,25-dihydroxyvitamin D: analysis by mathematical modeling PloS one, 2012; 7(1): e30773.
Chen Hong, Gilbert Linda C, Lu X, Liu Zhaofan, You Shaojin, Weitzmann M Neale, Nanes Mark S, Adams John   A new regulator of osteoclastogenesis: estrogen response element-binding protein in bone Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 2011; 26(10): 2537-47.
Walker Valencia P, Zhang Xiaoran, Rastegar Ida, Liu Philip T, Hollis Bruce W, Adams John S, Modlin Robert L   Cord blood vitamin D status impacts innate immune responses The Journal of clinical endocrinology and metabolism, 2011; 96(6): 1835-43.
Lisse Thomas S, Liu Ting, Irmler Martin, Beckers Johannes, Chen Hong, Adams John S, Hewison Martin   Gene targeting by the vitamin D response element binding protein reveals a role for vitamin D in osteoblast mTOR signaling FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2011; 25(3): 937-47.
Lisse Thomas S, Hewison Martin, Adams John S   Hormone response element binding proteins: novel regulators of vitamin D and estrogen signaling Steroids, 2011; 76(4): 331-9.
Chun Rene F, Adams John S, Hewison Martin   Immunomodulation by vitamin D: implications for TB Expert review of clinical pharmacology, 2011; 4(5): 583-91.
Zou Xuan, Shen Jia, Chen Feng, Ting Kang, Zheng Zhong, Pang Shen, Zara Janette N, Adams John S, Soo Chia, Zhang Xinli   NELL-1 binds to APR3 affecting human osteoblast proliferation and differentiation FEBS letters, 2011; 585(15): 2410-8.
Lake Jordan E, Adams John S   Vitamin D in HIV-Infected Patients Current HIV/AIDS reports, 2011; 8(3): 133-41.
Fabri Mario, Stenger Steffen, Shin Dong-Min, Yuk Jae-Min, Liu Philip T, Realegeno Susan, Lee Hye-Mi, Krutzik Stephan R, Schenk Mirjam, Sieling Peter A, Teles Rosane, Montoya Dennis, Iyer Shankar S, Bruns Heiko, Lewinsohn David M, Hollis Bruce W, Hewison Martin, Adams John S, Steinmeyer Andreas, Zügel Ulrich, Cheng Genhong, Jo Eun-Kyeong, Bloom Barry R, Modlin Robert L   Vitamin D is required for IFN-gamma-mediated antimicrobial activity of human macrophages Science translational medicine, 2011; 3(104): 104ra102.
Lagishetty Venu, Chun Rene F, Liu Nancy Q, Lisse Thomas S, Adams John S, Hewison Martin   1alpha-hydroxylase and innate immune responses to 25-hydroxyvitamin D in colonic cell lines The Journal of steroid biochemistry and molecular biology, 2010; 121(1-2): 228-33.
Bernthal Nicholas M, Stavrakis Alexandra I, Billi Fabrizio, Cho John S, Kremen Thomas J, Simon Scott I, Cheung Ambrose L, Finerman Gerald A, Lieberman Jay R, Adams John S, Miller Lloyd S   A mouse model of post-arthroplasty Staphylococcus aureus joint infection to evaluate in vivo the efficacy of antimicrobial implant coatings PloS one, 2010; 5(9): e12580.
Hokugo Akishige, Christensen Russell, Chung Evelyn M, Sung Eric C, Felsenfeld Alan L, Sayre James W, Garrett Neal, Adams John S, Nishimura Ichiro   Increased prevalence of bisphosphonate-related osteonecrosis of the jaw with vitamin D deficiency in rats Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 2010; 25(6): 1337-49.
Edfeldt Kristina, Liu Philip T, Chun Rene, Fabri Mario, Schenk Mirjam, Wheelwright Matthew, Keegan Caroline, Krutzik Stephan R, Adams John S, Hewison Martin, Modlin Robert L   T-cell cytokines differentially control human monocyte antimicrobial responses by regulating vitamin D metabolism Proceedings of the National Academy of Sciences of the United States of America, 2010; 107(52): 22593-8.
Adams John S, Hewison Martin   Update in vitamin D The Journal of Clinical Endocrinology and Metabolism, 2010; 95(2): 471-8.
Lagishetty Venu, Misharin Alexander V, Liu Nancy Q, Lisse Thomas S, Chun Rene F, Ouyang Yi, McLachlan Sandra M, Adams John S, Hewison Martin   Vitamin D deficiency in mice impairs colonic antibacterial activity and predisposes to colitis Endocrinology, 2010; 151(6): 2423-32.
Hewison Martin, Adams John S   Vitamin D insufficiency and skeletal development in utero Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 2010; 25(1): 11-3.
Chun Rene F, Lauridsen Anna L, Suon Lizabeth, Zella Lee A, Pike J Wesley, Modlin Robert L, Martineau Adrian R, Wilkinson Robert J, Adams John, Hewison Martin   Vitamin D-binding protein directs monocyte responses to 25-hydroxy- and 1,25-dihydroxyvitamin D The Journal of clinical endocrinology and metabolism, 2010; 95(7): 3368-76.
Montoya Dennis, Cruz Daniel, Teles Rosane M B, Lee Delphine J, Ochoa Maria Teresa, Krutzik Stephan R, Chun Rene, Schenk Mirjam, Zhang Xiaoran, Ferguson Benjamin G, Burdick Anne E, Sarno Euzenir N, Rea Thomas H, Hewison Martin, Adams John S, Cheng Genhong, Modlin Robert L   Divergence of macrophage phagocytic and antimicrobial programs in leprosy Cell host & microbe, 2009; 6(4): 343-53.
Chen Hong, Clemens Thomas L, Hewison Martin, Adams John S   Estradiol and tamoxifen mediate rescue of the dominant-negative effects of estrogen response element-binding protein in vivo and in vitro Endocrinology, 2009; 150(5): 2429-35.
Adams John S, Ren Songyang, Liu Philip T, Chun Rene F, Lagishetty Venu, Gombart Adrian F, Borregaard Niels, Modlin Robert L, Hewison Martin   Vitamin d-directed rheostatic regulation of monocyte antibacterial responses Journal of immunology (Baltimore, Md. : 1950), 2009; 182(7): 4289-95.
Liu Nancy, Nguyen Lisa, Chun Rene F, Lagishetty Venu, Ren Songyang, Wu Shaoxing, Hollis Bruce, DeLuca Hector F, Adams John S, Hewison Martin   Altered endocrine and autocrine metabolism of vitamin D in a mouse model of gastrointestinal inflammation Endocrinology, 2008; 149(10): 4799-808.
Chun Rene F, Adams John S, Hewison Martin   Back to the future: a new look at ‘old’ vitamin D The Journal of endocrinology, 2008; 198(2): 261-9.
Krutzik Stephan R, Hewison Martin, Liu Philip T, Robles Juan Antonio, Stenger Steffen, Adams John S, Modlin Robert L   IL-15 links TLR2/1-induced macrophage differentiation to the vitamin D-dependent antimicrobial pathway Journal of Immunology , 2008; 181(10): 7115-20.
Geller Jordan L, Hu Bei, Reed Susan, Mirocha James, Adams John S   Increase in bone mass after correction of vitamin D insufficiency in bisphosphonate-treated patients Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists, 2008; 14(3): 293-7.
Adams John S, Hewison Martin   Unexpected actions of vitamin D: new perspectives on the regulation of innate and adaptive immunity Nature clinical practice. Endocrinology & Metabolism, 2008; 4(2): 80-90.
Geller Jordan L, Adams John S   Vitamin D therapy Current osteoporosis reports, 2008; 6(1): 5-11.
Lee Jay M, Pou Karla, Sadow Peter M, Chen Hong, Hu Bei, Hewison Martin, Adams John S, Sugarbaker David J, Fisher Naomi D L   Vitamin D-mediated hypercalcemia and Cushing syndrome as manifestations of malignant pleural mesothelioma Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists, 2008; 14(8): 1011-6.
Geller Jordan L, Khosravi Azarmindokht, Kelly Marilyn H, Riminucci Mara, Adams John S, Collins Michael T   Cinacalcet in the management of tumor-induced osteomalacia Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 2007; 22(6): 931-7.
Hewison Martin, Burke Fiona, Evans Katie N, Lammas David A, Sansom David M, Liu Philip, Modlin Robert L, Adams John S   Extra-renal 25-hydroxyvitamin D3-1alpha-hydroxylase in human health and disease The Journal of Steroid Biochemistry and Molecular Biology, 2007; 103(3-5): 316-21.
Geller Jordan L, Adams John S   Proton pump inhibitor therapy and hip fracture risk JAMA : the journal of the American Medical Association, 2007; 297(13): 1429; author reply 1429-30.
Wu S, Ren S, Nguyen L, Adams J S, Hewison M   Splice variants of the CYP27b1 gene and the regulation of 1,25-dihydroxyvitamin D3 production Endocrinology, 2007; 148(7): 3410-8.
Adams John S, Chen Hong, Chun Rene, Ren Songyang, Wu Shaoxing, Gacad Mercedes, Nguyen Lisa, Ride Jonathan, Liu Philip, Modlin Robert, Hewison Martin   Substrate and enzyme trafficking as a means of regulating 1,25-dihydroxyvitamin D synthesis and action: the human innate immune response Journal of Bone and Mineral Research, 2007; 22 Suppl 2(2): V20-4.
Adams J S   Vitamin D as a defensin Journal of musculoskeletal & neuronal interactions, 2007; 6(4): 344-6.
Adams John S, Liu Philip T, Chun Rene, Modlin Robert L, Hewison Martin   Vitamin D in defense of the human immune response Annals of the New York Academy of Sciences, 2007; 1117(1): 94-105.
Chen Hong, Hewison Martin, Adams John S   Functional characterization of heterogeneous nuclear ribonuclear protein C1/C2 in vitamin D resistance: a novel response element-binding protein The Journal of Biological Chemistry, 2006; 281(51): 39114-20.
Geller Jordan L, Adams John S   Statins and fracture: are all variables accounted for? Archives of internal medicine, 2006; 166(9): 1041; author reply 1041-2.
Liu Philip T, Stenger Steffen, Li Huiying, Wenzel Linda, Tan Belinda H, Krutzik Stephan R, Ochoa Maria Teresa, Schauber Jürgen, Wu Kent, Meinken Christoph, Kamen Diane L, Wagner Manfred, Bals Robert, Steinmeyer Andreas, Zügel Ulrich, Gallo Richard L, Eisenberg David, Hewison Martin, Hollis Bruce W, Adams John S, Bloom Barry R, Modlin Robert L   Toll-like receptor triggering of a vitamin D-mediated human antimicrobial response Science , 2006; 311(5768): 1770-3.
Abreu Maria T, Geller Jordan L, Vasiliauskas Eric A, Kam Lori Y, Vora Puja, Martyak Lenna A, Yang Huiying, Hu Bei, Lin Ying-Chao, Keenan Gregory, Price Joanne, Landers Carol J, Adams John S, Targan Stephan R   Treatment with infliximab is associated with increased markers of bone formation in patients with Crohn’s disease Journal of clinical gastroenterology, 2006; 40(1): 55-63.
Karakelides Helen, Geller Jordan L, Schroeter Arnold L, Chen Hong, Behn Philip S, Adams John S, Hewison Martin, Wermers Robert A   Vitamin D-mediated hypercalcemia in slack skin disease: evidence for involvement of extrarenal 25-hydroxyvitamin D 1alpha-hydroxylase Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 2006; 21(9): 1496-9.
Adams John S   “Bound” to work: the free hormone hypothesis revisited Cell, 2005; 122(5): 647-9.
Chun Rene, Gacad Mercedes A, Hewison Martin, Adams John S   Adenosine 5′-triphosphate-dependent vitamin D sterol binding to heat shock protein-70 chaperones Endocrinology, 2005; 146(12): 5540-4.
Ren Songyang, Nguyen Lisa, Wu Shaoxing, Encinas Carlos, Adams John S, Hewison Martin   Alternative splicing of vitamin D-24-hydroxylase: a novel mechanism for the regulation of extrarenal 1,25-dihydroxyvitamin D synthesis The Journal of biological chemistry, 2005; 280(21): 20604-11.
Townsend Kelly, Evans Katie N, Campbell Moray J, Colston Kay W, Adams John S, Hewison Martin   Biological actions of extra-renal 25-hydroxyvitamin D-1alpha-hydroxylase and implications for chemoprevention and treatment The Journal of steroid biochemistry and molecular biology, 2005; 97(1-2): 103-9.
Chen Hong, Stuart William, Hu Bing, Nguyen Lisa, Huang Ganghua, Clemens Thomas L, Adams John S   Creation of estrogen resistance in vivo by transgenic overexpression of the heterogeneous nuclear ribonucleoprotein-related estrogen response element binding protein Endocrinology, 2005; 146(10): 4266-73.
Chen Hong, Hewison Martin, Hu Bing, Sharma Manju, Sun Zijie, Adams John S   An Hsp27-related, dominant-negative-acting intracellular estradiol-binding protein The Journal of biological chemistry, 2004; 279(29): 29944-51.
Li Xiaohui, Chen Sako, Kantorovich Vitaly, Cheng Li S C, Cohn Dan H, Rotter Jerome I, Yang Huiying, Adams John S   Genetic determinants of osteoporosis susceptibility in a female Ashkenazi Jewish population Genetics in medicine : official journal of the American College of Medical Genetics, 2004; 6(1): 33-7.
Evans Katie N, Taylor Harris, Zehnder Daniel, Kilby Mark D, Bulmer Judith N, Shah Farah, Adams John S, Hewison Martin   Increased expression of 25-hydroxyvitamin D-1alpha-hydroxylase in dysgerminomas: a novel form of humoral hypercalcemia of malignancy The American journal of pathology, 2004; 165(3): 807-13.
Adams John S, Chen Hong, Chun Rene, Gacad Mercedes A, Encinas Carlos, Ren Songyang, Nguyen Lisa, Wu Shaoxing, Hewison Martin, Barsony Julia   Response element binding proteins and intracellular vitamin D binding proteins: novel regulators of vitamin D trafficking, action and metabolism The Journal of steroid biochemistry and molecular biology, 2004; 89-90(1-5): 461-5.
Hewison Martin, Zehnder Daniel, Chakraverty Ronjon, Adams John S   Vitamin D and barrier function: a novel role for extra-renal 1 alpha-hydroxylase Molecular and cellular endocrinology, 2004; 215(1-2): 31-8.
Chen Hong, Hewison Martin, Hu Bing, Adams John S   Heterogeneous nuclear ribonucleoprotein (hnRNP) binding to hormone response elements: a cause of vitamin D resistance Proceedings of the National Academy of Sciences of the United States of America, 2003; 100(10): 6109-14.
Adams J S, Chen H, Chun R F, Nguyen L, Wu S, Ren S Y, Barsony J, Gacad M A   Novel regulators of vitamin D action and metabolism: Lessons learned at the Los Angeles zoo Journal of cellular biochemistry, 2003; 88(2): 308-14.
Chen Hong, Hu Bing, Huang Gang-Hua, Trainor Amanda G, Abbott David H, Adams John S   Purification and characterization of a novel intracellular 17 beta-estradiol binding protein in estrogen-resistant New World primate cells The Journal of clinical endocrinology and metabolism, 2003; 88(1): 501-4.
Hewison Martin, Kantorovich Vitaly, Liker Harley R, Van Herle Andre J, Cohan Pejman, Zehnder Daniel, Adams John S   Vitamin D-mediated hypercalcemia in lymphoma: evidence for hormone production by tumor-adjacent macrophages Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 2003; 18(3): 579-82.
Kantorovich Vitaly, Adams John S, Gaines Jade E, Guo Xiuqing, Pandian Murugan R, Cohn Daniel H, Rude Robert K   Genetic heterogeneity in familial renal magnesium wasting The Journal of clinical endocrinology and metabolism, 2002; 87(2): 612-7.
Hill Jennifer A, Goldin Jonathan G, Gjertson David, Emerick Aletha M, Greaser Lloyd D, Yoon Hyo-Chun, Khorrami Shauna, Aziz Donya, Adams John S   Progression of coronary artery calcification in patients taking alendronate for osteoporosis Academic radiology, 2002; 9(10): 1148-52.
Wu Shaoxing, Chun Rene, Gacad Mercedes A, Ren Songyang, Chen Hong, Adams John S   Regulation of 1,25-dihydroxyvitamin d synthesis by intracellular vitamin d binding protein-1 Endocrinology, 2002; 143(10): 4135.
Chun R F, Chen H, Boldrick L, Sweet C, Adams J S   Cloning, sequencing, and functional characterization of the vitamin D receptor in vitamin D-resistant New World primates American journal of primatology, 2001; 54(2): 107-18.
Henderson L B, Adams J S, Goldstein D R, Braunstein G D, Rotter J I, Scheuner M T   A familial risk profile for osteoporosis Genetics in medicine : official journal of the American College of Medical Genetics, 2000; 2(4): 222-5.
Kantorovich V, Gacad M A, Seeger L L, Adams J S   Bone mineral density increases with vitamin D repletion in patients with coexistent vitamin D insufficiency and primary hyperparathyroidism The Journal of clinical endocrinology and metabolism, 2000; 85(10): 3541-3.
Wu S, Ren S, Chen H, Chun R F, Gacad M A, Adams J S   Intracellular vitamin D binding proteins: novel facilitators of vitamin D-directed transactivation Molecular endocrinology (Baltimore, Md.), 2000; 14(9): 1387-97.
Chen H, Hu B, Allegretto E A, Adams J S   The vitamin D response element-binding protein. A novel dominant-negative regulator of vitamin D-directed transactivation The Journal of biological chemistry, 2000; 275(45): 35557-64.
Adams J S, Kantorovich V   Inability of short-term, low-dose hydroxychloroquine to resolve vitamin D-mediated hypercalcemia in patients with B-cell lymphoma The Journal of clinical endocrinology and metabolism, 1999; 84(2): 799-801.
Adams J S, Song C F, Kantorovich V   Rapid recovery of bone mass in hypercalciuric, osteoporotic men treated with hydrochlorothiazide Annals of internal medicine, 1999; 130(8): 658-60.
Adams J S, Kantorovich V, Wu C, Javanbakht M, Hollis B W   Resolution of vitamin D insufficiency in osteopenic patients results in rapid recovery of bone mineral density The Journal of clinical endocrinology and metabolism, 1999; 84(8): 2729-30.
Gacad M A, Adams J S   Proteins in the heat shock-70 family specifically bind 25-hydroxyvitamin D3 and 17beta-estradiol The Journal of clinical endocrinology and metabolism, 1998; 83(4): 1264-7.
Adams J S, Lee G   Gains in bone mineral density with resolution of vitamin D intoxication Annals of internal medicine, 1997; 127(3): 203-6.
Chen H, Arbelle J E, Gacad M A, Allegretto E A, Adams J S   Vitamin D and gonadal steroid-resistant New World primate cells express an intracellular protein which competes with the estrogen receptor for binding to the estrogen response element The Journal of clinical investigation, 1997; 99(4): 669-75.
More S Y, Adams S Y, Bandler S Y, Brouër S Y, Lanou S Y, Maris S Y, Seidel S Y   Phonon amplification using evaporation and adsorption of helium Physical review. B, Condensed matter, 1996; 54(1): 534-544.
Adams J S, Ren S Y, Arbelle J E, Shany S, Gacad M A   Coordinate regulation of nitric oxide and 1,25-dihydroxyvitamin D production in the avian myelomonocytic cell line HD-11 Endocrinology, 1995; 136(5): 2262-9.
Adams J S, Ren S Y, Arbelle J E, Horiuchi N, Gray R W, Clemens T L, Shany S   Regulated production and intracrine action of 1,25-dihydroxyvitamin D3 in the chick myelomonocytic cell line HD-11 Endocrinology, 1994; 134(6): 2567-73.
Gacad M A, Adams J S   Identification of a competitive binding component in vitamin D-resistant New World primate cells with a low affinity but high capacity for 1,25-dihydroxyvitamin D3 Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 1993; 8(1): 27-35.
Shany S, Ren S Y, Arbelle J E, Clemens T L, Adams J S   Subcellular localization and partial purification of the 25-hydroxyvitamin D3 1-hydroxylation reaction in the chick myelomonocytic cell line HD-11 Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 1993; 8(3): 269-76.
Zhou Rui, Park Juw Won, Chun Rene F, Lisse Thomas S, Garcia Alejandro J, Zavala Kathryn, Sea Jessica L, Lu Zhi-Xiang, Xu Jianzhong, Adams John S, Xing Yi, Hewison Martin   Concerted effects of heterogeneous nuclear ribonucleoprotein C1/C2 to control vitamin D-directed gene transcription and RNA splicing in human bone cells Nucleic acids research, 2017; 45(2): 606-618.
Hegde Vishal, Dworsky Erik M, Stavrakis Alexandra I, Loftin Amanda H, Zoller Stephen D, Park Howard Y, Richman Sherif, Johansen Daniel, Hu Yan, Taylor Julie A, Hamad Christopher D, Chun Rene F, Xi Weixian, Adams John S, Bernthal Nicholas M   Single-Dose, Preoperative Vitamin-D Supplementation Decreases Infection in a Mouse Model of Periprosthetic Joint Infection The Journal of bone and joint surgery. American volume, 2017; 99(20): 1737-1744.
Shieh Albert, Ma Christina, Chun Rene F, Witzel Sten, Rafison Brandon, Contreras Hannah T M, Wittwer-Schegg Jonas, Swinkels Leon, Huijs Tonnie, Hewison Martin, Adams John S   Effects of Cholecalciferol vs Calcifediol on Total and Free 25-Hydroxyvitamin D and Parathyroid Hormone The Journal of clinical endocrinology and metabolism, 2017; 102(4): 1133-1140.